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- Non-culprit vessel: >40 mm of proximal coronary artery Secondary Objective •To determine the effects of rosuvastatin on fibrous cap thickness of coronary plaque in a non-intervened coronary segment. Specifically, the change from baseline in OCT cap thickness at the end of week 52 Intravascular optical coherence tomography (OCT) can add value to angiography as a diagnostic and/or intervention tool for percutaneous coronary intervention (PCI) guidance. In diagnostic terms, it is essential to separate two very distinct populations: Stable coronary artery disease (CAD) and acute coronary syndromes (ACS)

acute coronary syndrome Drug Monograph. Gold Standard. Published October 23, 2018. Graphic original Mechanism, dosing, and adverse effects. 12 PCSK9 inhibitors Microsoft PowerPoint - Preventative Cardiology Final - Handout.ppt [Compatibility Mode]. •Coronary anatomy is just one side of the coin •There is complex interrelation between the structure and function of the coronary circulation, not only under physiologic circumstances in healthy persons (vessel size/perfusion area relation, endothelium, regulation of coronary blood flow), but also unde Figure 3. A, Irregular lesion in the circumflex coronary artery (yellow arrow).B and C, Optical coherence tomography (OCT) revealing multiple cavities.D, OCT showed a good final result.E, Angiography after bioresorbable vascular scaffold implantation.F, Longitudinal view.. Previous histopathologic studies demonstrated that old coronary thrombi undergo organization or recanalization Optical coherence tomography has become established as an imaging modality in clinical ophthalmology and is finding applications in even gastrointestinal and dermatological arenas. Its biggest application in cardiovascular medicine currently is in the coronary vasculature and to a lesser extent coronary graft assessment

Intravascular OCT in PCI - American College of Cardiolog

  1. e patency of grafts (not great for severe native disease) •Congenital anomalies of the coronary circulation •Coronary or pulmonary venous anatom
  2. This Consensus Document is the first of two reports summarizing the views of an expert panel organized by the European Association of Percutaneous Cardiovascular Interventions (EAPCI) on the clinical use of intracoronary imaging including intravascular ultrasound (IVUS) and optical coherence tomogra
  3. In 2015, Li et al. showed an advanced IVUS-OCT prototype that acquired IVUS-OCT images with a frame rate of 72 fps, enabling assessment of a 72-mm coronary artery segment in 4 s; the prototype was validated in vivo in the aortas of atherosclerotic rabbits and ex vivo in cadaveric human coronary arteries . In 2018, the first clinical use of.
  4. imum stent area after PCI—between the two strategies (p=0·12)
  5. OCT has been shown to be superior to both IVUS and coronary angioscopy in identifying plaque rupture, erosion, and coronary thrombus. 10 This ability to differentiate between plaque erosion and plaque rupture may provide future opportunities for risk stratification and targeted therapy in acute coronary syndrome (ACS). 11,12 Indeed, it has been.
Final thrombus burden

Personalize the treatment path for every patient. Our leading coronary imaging, physiology and therapy devices enable health care providers to optimize and streamline percutaneous coronary interventions (PCIs). Decide, guide, treat and confirm the right therapy for each patient at the point of care using our integrated solutions In one small 70-patient randomized, blinded, comparison of IVUS versus OCT study with crossover imaging, IVUS guidance was associated with greater stent expansion (minimum stent area of 7.1 vs. 6.1 mm 2, p = 0.04) and a smaller stent-edge plaque burden (proximal edge 37.1 vs. 45.7%, p = 0.001; distal edge 33.3 vs. 40.3%, p < 0.001) compared.

Optical Coherence Tomography Findings in Patients With

Optical coherence tomography (OCT) is an imaging technique that uses low-coherence light to capture micrometer-resolution, two- and three-dimensional images from within optical scattering media (e.g., biological tissue). It is used for medical imaging and industrial nondestructive testing (NDT). Optical coherence tomography is based on low-coherence interferometry, typically employing near. Optical coherence tomography (OCT) was done to assess whether the stenosis in the first diagonal artery was the culprit stenosis. A ruptured thin cap fibrous atheroma with overlying thrombus was identified in the first diagonal artery, showing an actively developing acute coronary syndrome (figure). Full-Text Coronary-artery bypass grafting (CABG) reduces the risk of death in patients with extensive coronary artery disease. 1 CABG is usually performed with the use of a cardiopulmonary bypass (on-pump.

Introduction. Anomalies of the coronary arteries are an uncommon category of cardiac disease. The prevalence is usually cited as 1%-2% of the general population (1,2).However, if a broad definition of coronary artery anomalies is considered, including more common variants such as myocardial bridging, then the prevalence is much higher (3,4).. Fourier domain optical coherence tomography (FD-OCT) is a novel near-infrared intravascular imaging modality with ∼10-fold greater axial resolution (∼15 μm) than IVUS.7, 8 Assessment of coronary artery dimensions by FD-OCT is accurate9 and reproducible.10 Postmortem data11, 12 and case reports suggest that FD-OCT may afford enhanced. Computed tomography (CT) plays an important supplementary role in the evaluation of patients with congenital heart disease (CHD). Fast multisection spiral CT can be used to obtain isotropic volume data, and high-quality two- and three-dimensional multiplanar reformatted images can be created to accurately and systematically delineate the normal and pathologic morphologic features of the. Optical coherence tomography. The in vivo visualisation of vulnerable plaque is now enhanced with high-resolution imaging. With its high resolution and ability to detect the lumen diameter in relation to vulnerable plaques and stents characteristics such as struts apposition and tissue coverage, the OCT can provide additional information not possible with other invasive coronary imaging. OCT is an innovative intravascular imaging tool that can be used to examine coronary atherosclerotic lesions at a resolution (10-15 μm) that far exceeds existing standards, such as.

October 18, 2017 Novo NordiGk . co-2 Acute coronary or cerebrovascular event 90 days before randomization Heart failure, New York Heart Association class IV PowerPoint Presentation. What is it? Starting October 1, year-round AQI forecasts for particles will be provided in local weathercasts in addition to the summertime ozone forecasts. But it also includes people with heart disease such as coronary artery disease or congestive heart failure. PowerPoint Presentation Author: Lesley Williams Last modified by: Meg. 5 Coronary Artery Size • IVUS of Coronary Arteries of 50 male and 25 female patients • Sex is an independent predictor of coronary arterial area (LM, LAD). • Study of Transplant patients (n=86) • Proximal LAD vessel area increased in all groups • Same gender and male donor to female recipient transplanted hearts, change in vessel size was small Optical coherence tomography (OCT) can be used to confirm the mechanism of acute coronary syndrome. OCT reveals coronary artery wall microstructure at vasospastic sites. Coronary vasospasm and non-ST-segment elevation myocardial infarction can both cause elevation of troponin and present with typical features of chest pain Coronary, Peripheral, and Neurovascular Guidewires - Performance Tests and Food and Drug Administration Staff Document issued on October 10, 2019. For questions about this document, contact

I25.812 Atherosclerosis of bypass graft of coronary artery of transplanted heart without angina pectoris I25.82 Chronic total occlusion of coronary artery I25.83 Coronary atherosclerosis due to lipid rich plaque I25.84 Coronary atherosclerosis due to calcified coronary lesion I25.89 Other forms of chronic ischemic heart diseas Thursday, October 19, 2017 12:00-1:00 Old Medical School Auditorium From Reaction to Readiness: Dealing with Challenging People Friday, October 20, 2017 8:30 -9:30 a.m. Old Ivy Road Healthy Gut, Healthy Brain: Stress, Inflammation and Resilience Tuesday, October 31, 2017 12:00-1:0

New guidelines for the diagnosis and management of chronic coronary syndromes (CCS) 1 were released during the 2019 European Society of Cardiology (ESC) Congress. The new guidelines were discussed in multiple sessions with different formats across the congress; this review summarises some of the discussion among experts at the congress around what the new guidelines mean for the way they. Cardiac catheterization/coronary angiography is considered the medical standard for evaluating ventricular function, assessing valvular heart disease and coronary artery anatomy for patients with known or suspected heart disease. Diagnostic cardiac catheterization underwent an enormous change in 2011. These changes were due to the work done by a committee that was doing a 5-year review on [ Optical coherence tomography (OCT) is a non- invasive optical imaging technique that uses low-power infrared laser light to image up to 2 mm beneath the skin surface. The clinician can obtain real-time images of the architecture of the skin without pretreatment or gels. OCT has been shown to be a useful diagnostic tool in diagnosing early stage.

FFR and iFR Work Together. FFR and iFR work together seamlessly on one system console, utilizing the same pressure wire and providing dual modality. With the introduction of iFR, interventional cardiologists now have more choices; and with the flip of a switch, the iFR modality provides a hyperemia-free measurement anatomy. For these reasons, coronary arteriography should be considered in almost all patients with suspected coronary atherosclerosis.32-34 Fractional flow reserve, intravascular ultra-sound and optical coherence tomography may provide addition-al information in certain cases. Molecular imaging that will b This article illustrates common artifacts encountered at cardiac CT, details the physics behind their origin, and describes methods to minimize or eliminate these artifacts. A summary of CT artifacts with causes and solutions is provided in Table 1. Table 1: Overview of Common CT Artifacts and Their Appearance, Causes, and Solutions Background / Objectives Automatic algorithms for stent struts segmentation in optical coherence tomography (OCT) images of coronary arteries have been developed over the years, particularly with application on metallic stents. The aim of this study is three-fold: (1) to develop and to validate a segmentation algorithm for the detection of both lumen contours and polymeric bioresorbable. Intravascular optical coherence tomography (iOCT) is being used to assess viability of new coronary artery stent designs. We developed a highly automated method for detecting stent struts and measuring tissue coverage. We trained a bagged decision trees classifier to classify candidate struts using features extracted from the images. With 12 best features identified by forward selection.

The Optical Coherence Tomography Versus Intravascular Ultrasound Guided Percutaneous Coronary Intervention (OCTIVUS) trial (NCT03394079) is a prospective, open-label, multicenter, dual arm, and randomized trial to establish that OCT-guided PCI is non-inferior to IVUS-guided PCI regarding target vessel failures at 1 year Spontaneous coronary artery dissection is an increasingly recognised cause of acute coronary syndromes, especially in young and middle-age women. Recognising its particularities and differences with atherosclerotic disease is central for appropriately identifying and approaching these patients. The authors review the current state of knowledge on spontaneous coronary artery dissection and. A new section titled Coronary Therapeutic Services and Procedures was added to the Medicine section of the 2013 CPT manual. This new section introduces new codes 92920-92944 for coronary angioplasty, coronary atherectomy and placement of intracoronary stents in the coronary arteries and coronary artery bypass grafts. These new codes replace codes 92980-92984 & 92995-92996. The [

Video: Optical Coherence Tomography - The Cardiology Adviso

Percutaneous coronary intervention (PCI) improves symptoms and clinical outcome in patients who have acute coronary syndrome (ACS), i.e., who are hospitalized and undergo coronary angiography. Background: Conventional contrast cineangiography and intravascular ultrasound (IVUS) provide a limited definition of vessel microstructure and are unable to evaluate dissection, tissue prolapse, and stent apposition on a size scale less than 100 μm. Objective: To evaluate the use of intravascular optical coherence tomography (OCT) to assess the coronary arteries in patients undergoing. In vivo association between positive coronary artery remodelling and coronary plaque characteristics assessed by intravascular optical coherence tomograph A coronary computed tomography angiogram (CTA) uses advanced CT technology, along with intravenous (IV) contrast material (dye), to obtain high-resolution, 3D pictures of the moving heart and great vessels. Get the latest information about heart & vascular disorders, treatments, tests and prevention from the No. 1-ranked heart program in the United States A total of 109 patients had a cardiovascular event, with event rates of 4.9% with omeprazole and 5.7% with placebo (hazard ratio with omeprazole, 0.99; 95% CI, 0.68 to 1.44; P=0.96); high-risk.

† IVUS catheters for coronary applications †† IVUS catheters for peripheral applications. By clicking on the link, you will be leaving the official Royal Philips Healthcare (Philips) website. Any links to third-party websites that may appear on this site are provided only for your convenience and in no way represent any affiliation or. A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee to Update the 1999 Guidelines for Coronary Artery Bypass Graft Surgery). J Am. Intravascular ultrasound (IVUS) is a medical imaging methodology using a specially designed catheter with a miniaturized ultrasound probe attached to the distal end of the catheter. The proximal end of the catheter is attached to computerized ultrasound equipment. It allows the application of ultrasound technology, such as piezoelectric transducer or CMUT, to see from inside blood vessels out. Coronary artery stents are tiny wire-mesh tubes that are used during one kind of operation for coronary artery disease. These stents are placed into the narrow coronary artery during a procedure called balloon angioplasty (the more accurate medical name for this is percutaneous transluminal coronary angioplasty, or PTCA for short). A sten

Goldsmith JR, Aronow WS. Carbon monoxide and coronary heart disease: A review. Environ Res. 1975 Oct; 10 (2):236-248. Grice HC, Goodman T, Munro IC, Wiberg GS, Morrison AB. Myocardial toxicity of cobalt in the rat. Ann N Y Acad Sci. 1969 Jan 31; 156 (1):189-194. Harris WS. Toxic effects of aerosol propellants on the heart Patients with acute coronary syndrome (ACS) commonly are classified into two groups to facilitate evaluation and management, namely patients with acute myocardial infarction with ST-segment elevation (STEMI) on their presenting electrocardiogram (ECG) and those with non-ST-segment elevation acute coronary syndrome (NSTE-ACS). The latter include patients with non-ST-segment elevation myocardial.

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Eikelboom JW, Anand SS, Malmberg K, et al. Unfractionated heparin and low-molecular-weight heparin in acute coronary syndrome without ST elevation: a meta-analysis. Lancet 2000; 355:1936. Low-molecular-weight heparin during instability in coronary artery disease, Fragmin during Instability in Coronary Artery Disease (FRISC) study group The presence of cholesterol crystals is a hallmark of atherosclerosis, but until recently, such crystals have been considered to be passive components of necrotic plaque cores. Recent studies have demonstrated that phagocytosis of cholesterol crystals by macrophages may actively precipitate plaque progression via an inflammatory pathway, emphasizing the need for methods to study the. Coronary angiograms are part of a general group of procedures known as heart (cardiac) catheterizations. Cardiac catheterization procedures can both diagnose and treat heart and blood vessel conditions. A coronary angiogram, which can help diagnose heart conditions, is the most common type of cardiac catheterization procedure

IVUS vs. OCT: What to Use When tctmd.co

Kubo, T. et al. Assessment of culprit lesion morphology in acute myocardial infarction: ability of optical coherence tomography compared with intravascular ultrasound and coronary angioscopy. J. Am This is also called ischemia. It may be chronic, narrowing of the coronary artery over time and limiting of the blood supply to part of the muscle. Or it can be acute, resulting from a sudden rupture of a plaque and formation of a thrombus or blood clot. The traditional risk factors for coronary artery disease are high LDL cholesterol, low HDL. The Lipid Research Clinics Coronary Primary Prevention Trial (LRC-CPPT), was a multicenter, randomized, double-blind study, designed to test the efficacy of cholesterol lowering in reducing risk of coronary heart disease (CHD). Selected patients included 3,806 middle-aged men without clinically manifest coronary disease and with primary.

Optical Coherence Tomography to Optimize Results of

Angiography and OCT were adjudicated by independent core laboratories, and major adverse cardiac events were adjudicated by an independent clinical events committee. Between May 2018 to March 2019, 120 participants were enrolled in the study. The most common target vessel was the left anterior descending coronary artery (62.5%) Optical coherence tomography (an invasive technique) and contrast-enhanced coronary computed tomographic angiography (CCTA), a noninvasive technique , have shown that culprit lesions are composed of a lipid-rich core with a thin fibrous cap. Patients with NSTE-ACS frequently have multiple such plaques that are at risk of disruption (vulnerable.

OCT-guided Percutaneous Coronary Intervention in

Spontaneous coronary artery dissection (SCAD) is a non-traumatic and non-iatrogenic separation of the coronary arterial wall and is an infrequent cause of acute myocardial infarction. It is more common in younger patients and in women. Modern usage of the term SCAD denotes nonatherosclerotic causes, which is the focus of this topic Objectives To determine if coronary computed tomographic angiography enhances prediction of perioperative risk in patients before non-cardiac surgery and to assess the preoperative coronary anatomy in patients who experience a myocardial infarction after non-cardiac surgery. Design Prospective cohort study. Setting 12 centers in eight countries. Participants 955 patients with, or at risk of.

Cardiac optical coherence tomography Hear

The prognostic value of B-type natriuretic peptide in patients with acute coronary syndromes. N Engl J Med. 2001 Oct 4. 345(14):1014-21. . . James SK, Lindahl B, Siegbahn A, et al. N-terminal pro. Objective To assess the benefits and risks of short term (<12 months) or extended (>12 months) dual antiplatelet therapy (DAPT) versus standard 12 month therapy, following percutaneous coronary intervention with drug eluting stents. Design Meta-analysis of randomised controlled trials. Data sources PubMed, Embase, Cumulative Index to Nursing and Allied Health Literature, Scopus, Web of Science. The coronary arteries supply blood, oxygen and nutrients to your heart. A buildup of plaque can narrow these arteries, decreasing blood flow to your heart. Eventually, the reduced blood flow may cause chest pain (angina), shortness of breath, or other coronary artery disease signs and symptoms. A complete blockage can cause a heart attack Data Synthesis Coronary artery stents increase the safety of interventional procedures, increase procedure success rates, and decrease the need for emergency coronary artery bypass graft surgery. Conclusions Intracoronary stents have become an essential component of the catheter-based treatment of coronary artery disease. The evidence indicates.

Free Download Acute Coronary Syndromes PowerPoint

A Coronary Angiogram, which can help diagnose heart conditions, is the most common type of Cardiac Catheterization procedure. During a Coronary Angiogram, a form of dye that is detectable by an X-ray machine is injected into the blood vessels of your heart. The X-ray machine rapidly takes a series of images (angiograms), presenting a detailed. Conventional coronary angiography has limitations in detecting stent-related complications. This case highlights this limitation and illustrates how intracoronary imaging with optical coherence tomography helps in this situation. A 60-year-old man with stable angina underwent elective percutaneous coronary intervention to the right coronary artery (panel A)

Clinical use of intracoronary imaging

The public health and economic burdens of coronary artery disease (CAD) are substantial. A large proportion of ambulatory health care visits are for evaluation of patients with suspected CAD. Each year, an estimated 1.5 percent of the population presents to primary care providers with chest pain. Moreover, CAD is responsible for 8 to 10 percent of emergency department visits It has been over 30 years since Rubler et al. (1) described four diabetic patients with congestive heart failure (CHF), normal coronary arteries, and no other etiologies for CHF and proposed that it was due to diabetic cardiomyopathy. Eight years ago, I reviewed the evidence for diabetic cardiomyopathy as a unique entity unassociated with coronary artery disease and concluded that diabetic. Coronary artery disease s/p MI and stents x2, on ASA & Plavix. COPD/ chronic respiratory failure on home O2 since Nov. 2016. Atrial fibrillation (not on anti-coagulation) Social History. Smoked for 42 years; quit 6 years ago. No EtOH use. Patient: Ms. DR is a 62 yoF with history of tobacco us Chronic Stable Coronary Artery Disease: ACE Inhibitor or ARB Therapy - Diabetes or Left Ventricular Systolic Dysfunction (LVEF <40%)** American College of Cardiology. Claims/Clinical Data. 1. 0067. Chronic Stable Coronary Artery Disease: Antiplatelet Therapy** American College of Cardiology. Claims/Clinical Data. 1. 0119. Risk-Adjusted. Decline in deaths from coronary heart disease and stroke; and on Social Determinants of Health was adopted during the World Conference on Social Determinants of Health on 21 October 2011 and endorsed five priority areas. The declaration expresses global political commitment for the implementation of a social determinants of health approach.

Advances in IVUS/OCT and Future Clinical Perspective of

Optical coherence tomography (OCT) is a progressively accepted intravascular modality for studying coronary arteries. It provides unprecedented microstructural information regarding atherosclerotic plaques and placed stents, and has a high resolution capacity of 10 µm Optical coherence tomography (OCT) is a non-invasive imaging test. OCT uses light waves to take cross-section pictures of your retina. With OCT, your ophthalmologist can see each of the retina's distinctive layers. This allows your ophthalmologist to map and measure their thickness Optical coherence tomography (OCT) demonstrated an ulcer-like lesion in the proximal and superficial mixed thrombus with thin-cap fibroatheroma (TCFA) in the distal ().CTA and OCT strongly suggested plaque vulnerablity and a high possibility of no reflow during percutaneous coronary intervention.2 Using a distal protection device, we performed a balloon angioplasty and covered both plaques. Coronary Artery Disease. Coronary heart disease is the most common type of heart disease, killing 365,914 people in 2017. 4; About 18.2 million adults age 20 and older have CAD (about 6.7%). 3; About 2 in 10 deaths from CAD happen in adults less than 65 years old. Opium is a widely abused substance throughout the Middle East and Asia. In this Perspectives article, Dr Masoudkabir and colleagues dispel the commonly held misconception in these regions that.

Optical coherence tomography-guided PCI - The Lance

-- coronary artery calcification (Lewis et al., Psy Med, 2006) -- C-reactive protein (Lewis et al., Brain Beh Immunity, 2010) -- blood pressure (Lewis et al., J Gerontology: Bio Sci & Med Sci 2009 Heart disease is caused by atherosclerosis (ath-uh-roh-skluh-roh-sis), which is the buildup of fatty deposits, or plaques, in the walls of the coronary arteries over many years. The coronary arteries surround the outside of the heart and supply blood nutrients and oxygen to the heart muscle Here, optical coherence tomography was adapted to allow high-speed visualization of tissue in a living animal with a catheter-endoscope 1 millimeter in diameter. This method, referred to as optical biopsy, was used to obtain cross-sectional images of the rabbit gastrointestinal and respiratory tracts at 10-micrometer resolution

Value Of Intracoronary Imaging And Coronary PhysiologyPPT - Coronary Calcium Scoring for Risk Stratification andPPT - Pre-op and Post-op Beta Blockers PowerPointTen-Year Experience of Coronary Endarterectomy for thePPT - The use of Cardiac CT and MRI in Clinical Practice

New tomographic cardiovascular imaging tests, such as intravascular ultrasonography (IVUS), coronary computed tomography (CT) angiography and magnetic resonance imaging (MRI), can be used to assess atherosclerotic plaques for the characterization and early staging of coronary artery disease (CAD). Although IVUS images have very high resolution capable of revealing very early preclinical CAD. Each year, more than 600,000 persons will have their first MI, and nearly 300,000 patients with known coronary artery disease will have recurrence.4 MI is a subset of acute coronary syndrome (ACS. The public health and economic burdens of coronary artery disease (CAD) are substantial. A large proportion of ambulatory health care visits are for evaluation of patients with suspected CAD. Each year, an estimated 1.5 percent of the population presents to primary care providers with chest pain. Moreover, CAD is responsible for 8 to 10 percent of emergency department visits